4-Iodophenylacetonitrile → N-Hydroxy-2-(4-iodophenyl)acetimidamide

HRID 1717835Notes

Reaction equation

[OH:1][NH:2][C:3](=[NH:12])[CH2:4][C:5]1[CH:10]=[CH:9][CH:8]=[C:7](I)[CH:6]=1.[I:13]C1C=CC(CC#N)=CC=1>>[OH:1][NH:2][C:3](=[NH:12])[CH2:4][C:5]1[CH:10]=[CH:9][C:8]([I:13])=[CH:7][CH:6]=1

Participants

Reactant 2

HCID 1428664-Iodophenylacetonitrile

HCID 178510804N-Hydroxy-2-(3-iodo-phenyl)-acetamidine

Product 1

HCID 178510823N-Hydroxy-2-(4-iodophenyl)acetimidamide

Procedure

The title compound is prepared essentially as described for N-hydroxy-2-(3-iodo-phenyl)-acetamidine, employing (4-iodo-phenyl)-acetonitrile. LC-MS (m/e): 277 (M+1).

Sources & evidence

ORD record: ord-d923bfa64d6146b986740556729e9b4a
Source dataset: uspto-grants-2010_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07803938B2

Reaction notes

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