2-Chloro-6-methyl-3-nitropyridine → 2-{4-[3-(3,5-Difluorophenyl)prop-2-yn-yl]piperidin-1-yl}-6-methyl-3-nitropyridine
Reaction equation
[Cl:18][c:19]1[n:20][c:21]([CH3:28])[cH:22][cH:23][c:24]1[N+:25](=[O:26])[O-:27].[F:1][c:2]1[cH:3][c:4]([C:9]#[C:10][CH2:11][CH:12]2[CH2:13][CH2:14][NH:15][CH2:16][CH2:17]2)[cH:5][c:6]([F:8])[cH:7]1>>[F:1][c:2]1[cH:3][c:4]([C:9]#[C:10][CH2:11][CH:12]2[CH2:13][CH2:14][N:15]([c:19]3[n:20][c:21]([CH3:28])[cH:22][cH:23][c:24]3[N+:25](=[O:26])[O-:27])[CH2:16][CH2:17]2)[cH:5][c:6]([F:8])[cH:7]1Participants
3
Sources & evidence
- ORD record
- ord-6767e58b6249468c9aaa97386c2fb5fb
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
Loading…