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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 171878Generated: October 25, 2026

Tetrahydrofuran → methyl 5-amino-5-oxo-4-[3-oxo-7-[(2,4,6-trichlorophenyl)methoxy]-1H-isoindol-2-yl]pentanoate

https://huagongshe.com/reaction/171878

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantTriphenylphosphineHCID 11776—
ReactantDiisopropyl diazene-1,2-dicarboxylateHCID 75555—
Reactant2,4,6-Trichlorobenzyl alcoholHCID 4582574—
ReactantMethyl 5-amino-4-(4-hydroxy-1-oxoisoindolin-2-yl)-5-oxopentanoateHCID 58389139—
Productmethyl 5-amino-5-oxo-4-[3-oxo-7-[(2,4,6-trichlorophenyl)methoxy]-1H-isoindol-2-yl]pentanoateHCID 67334262—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (9/10)
ORD IDord-48b72d6688af4595a8759dada618ed8f
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (9/10)