HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Aminothiophenol → N-benzyloxycarbonyl-S-(2-aminophenyl)-beta-phenylcysteine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Aminothiophenol | HCID 8713 | — |
| Reactant | alpha-Benzyloxycarbonylamino-beta-phenylacrylic acid | HCID 53972564 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | N-benzyloxycarbonyl-S-(2-aminophenyl)-beta-phenylcysteine | HCID 13533189 | 9.5% |
Reaction Steps
20 g of α-benzyloxycarbonylamino-β-phenylacrylic acid and 10 g of o-aminobenzenethiol were mixed with 40 ml of ethanol and the resulting mixture was heated under reflux for 20 hours. After cooling to room temperature, the precipitated crystalline component was separated by filtration and washed with ethanol to obtain 2.7 g of crystals. This product decomposed at 198° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04539150 |
| Source dataset | uspto-grants-1985_09 |
| ORD ID | ord-5cc14afe26ad451da63add060ddf1931 |
| Source note | uspto-grants-1985_09 |