Chlorpromazine hydrochloride → Chlorpromazine

HRID 1719136Notes

Reaction equation

HRID 1719136 reaction equation
[CH3:1][N:2]([CH2:4][CH2:5][CH2:6][N:7]1[C:16]2[CH:17]=[C:18]([Cl:21])[CH:19]=[CH:20][C:15]=2[S:14][C:13]2[C:8]1=[CH:9][CH:10]=[CH:11][CH:12]=2)[CH3:3].Cl>O>[CH3:1][N:2]([CH2:4][CH2:5][CH2:6][N:7]1[C:16]2[CH:17]=[C:18]([Cl:21])[CH:19]=[CH:20][C:15]=2[S:14][C:13]2[C:8]1=[CH:9][CH:10]=[CH:11][CH:12]=2)[CH3:3]

Participants

3

Reactant 1

HCID 6240Chlorpromazine hydrochloride

Product 1

HCID 2726Chlorpromazine

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

100 g of chloropromazine hydrochloride [10-(3'-methylamino-propyl)-2-chloro-phenothiazine hydrochloride] (USP XX) is dissolved in 1 liter of deionized water and added at constant stirring to a solution of (NH4+)-polymethacrylate of the following composition:

Workup

  1. additionadded

Sources & evidence

ORD record
ord-60b151c0700749bdab5efbdba427de02
Source dataset
uspto-grants-1985_09
Patent number
US04539199

Reaction notes

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