HuagongsheHuagongshe Chemistry Print Report · For research reference only
(S)-[(2R,5R)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl]-(6-methoxyquinolin-4-yl)methanol;sulfuric acid → (S)-[(2R,5R)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl]-(6-methoxyquinolin-4-yl)methanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (S)-[(2R,5R)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl]-(6-methoxyquinolin-4-yl)methanol;sulfuric acid | HCID 12948 | — |
| Solvent | Water | HCID 962 | — |
| Product | (S)-[(2R,5R)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl]-(6-methoxyquinolin-4-yl)methanol | HCID 5953 | — |
Reaction Steps
100 g of quinidine bisulfate (6-methoxy-α-(5-vinyl-2-quinuclidinyl)-4-quinolinemethanol bisulfate) (Extra Pharmacopoeia Martindale XXVII Ed.) is dissolved in 1.5 liters of deionized water and added at constant stirring to a solution of sodium-polymethacrylate of the following composition:
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04539199 |
| Source dataset | uspto-grants-1985_09 |
| ORD ID | ord-9f941f37b0e1442f9d83a5341b54ccca |
| Source note | uspto-grants-1985_09 |