ethyl (2Z)-3-(pyridin-3-yl)but-2-enoate → HCID 12727116, compound

HRID 1719161Notes

Reaction equation

HRID 1719161 reaction equation
[N:1]1[CH:6]=[CH:5][CH:4]=[C:3](/[C:7](/[CH3:14])=[CH:8]\[C:9]([O:11][CH2:12][CH3:13])=[O:10])[CH:2]=1>C(O)C.[Pd]>[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([CH:7]([CH3:14])[CH2:8][C:9]([O:11][CH2:12][CH3:13])=[O:10])[CH:2]=1

Participants

4

Reactant 1

HCID 67402107ethyl (2Z)-3-(pyridin-3-yl)but-2-enoate

Product 1

HCID 12727116HCID 12727116, compoundYield 95.5%

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

Ethyl 3-(3-pyridyl)crotonate (13.2 g) was hydrogenated in ethanol (130 ml) at 270 kPa with 10% palladium on charcoal catalyst for 3 hours at room temperature to give ethyl 3-(3-pyridyl)butyrate (12.74 g), b.p. 74°-80°/0.15 mmHg.

Sources & evidence

ORD record
ord-dc502e21336d4570895534b95bdd0dcf
Source dataset
uspto-grants-1985_09
Patent number
US04539207

Reaction notes

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