HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-(((2-Aminoethyl)thio)methyl)-N,N-dimethyl-2-furanmethanamine → 2-[2-(5-Dimethylaminomethyl-2-furylmethylthio)ethylamino]-5-(1-(3-pyridyl)ethyl)-4-pyrimidone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-(((2-Aminoethyl)thio)methyl)-N,N-dimethyl-2-furanmethanamine | HCID 162203 | — |
| Reactant | 2-Methylthio-5-[1-(3-pyridyl)ethyl]-4-pyrimidone | HCID 13505309 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | 2-[2-(5-Dimethylaminomethyl-2-furylmethylthio)ethylamino]-5-(1-(3-pyridyl)ethyl)-4-pyrimidone | HCID 20213276 | — |
Reaction Steps
Equimolar amounts of 2-methylthio-5-[1-(3-pyridyl)ethyl]-4-pyrimidone and 2-(5-dimethylaminomethyl-2-furylmethylthio)ethylamine in pyridine are boiled under reflux for 48 hours and evaporated to dryness. The residue is purified to give 2-[2-(5-dimethylaminomethyl-2-furylmethylthio)ethylamino]-5-(1-(3-pyridyl)ethyl)-4-pyrimidone.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04539207 |
| Source dataset | uspto-grants-1985_09 |
| ORD ID | ord-2bc3632299774ad9beeb67c8fdcb4844 |
| Source note | uspto-grants-1985_09 |