HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-(((2-Aminoethyl)thio)methyl)-N,N-dimethyl-2-furanmethanamine → 2-[2-(5-Dimethylaminomethyl-2-furylmethylthio)ethylamino]-5-methyl-4-pyrimidone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-(((2-Aminoethyl)thio)methyl)-N,N-dimethyl-2-furanmethanamine | HCID 162203 | — |
| Reactant | 5-Methyl-2-(methylthio)pyrimidin-4(3H)-one | HCID 240575 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | 2-[2-(5-Dimethylaminomethyl-2-furylmethylthio)ethylamino]-5-methyl-4-pyrimidone | HCID 20213282 | — |
Reaction Steps
Reaction of 2-methylthio-5-methyl-4-pyrimidone with one equivalent of 2-(5-dimethylaminomethyl-2-furylmethylthio)ethylamine by boiling under reflux in pyridine for 48 hours gives 2-[2-(5-dimethylaminomethyl-2-furylmethylthio)ethylamino]-5-methyl-4-pyrimidone.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04539207 |
| Source dataset | uspto-grants-1985_09 |
| ORD ID | ord-151f0d755bf64648afda17ee6d52cd55 |
| Source note | uspto-grants-1985_09 |