HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl iodide → 5-Methoxy-1,2,3,4-tetrahydronaphthalene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl iodide | HCID 6328 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 5,6,7,8-Tetrahydro-1-naphthol | HCID 68258 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | 5-Methoxy-1,2,3,4-tetrahydronaphthalene | HCID 221171 | — |
Reaction Steps
5,6,7,8-Tetrahydro-1-naphthol (9.85 g, 66mM), methyl iodide (30.6 g, 215mM) and potassium carbonate (15 g, 90.8mM) in acetone (500 ml) were heated under reflux with stirring for 3 days. The mixture was evaporated and the residue was extracted with 2M sodium hydroxide and ether. The organic layer was washed and dried to give 1-methoxy-5,6,7,8-tetrahydronaphthalene as as oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04539319 |
| Source dataset | uspto-grants-1985_09 |
| ORD ID | ord-9ab89f5c1a154a34a41fb6f5e5631fd1 |
| Source note | uspto-grants-1985_09 |