HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Benzyloxy-5,6,7,8-tetrahydro-1-naphthonitrile → 4-Hydroxy-5,6,7,8-tetrahydronaphthalene-1-carbonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Benzyloxy-5,6,7,8-tetrahydro-1-naphthonitrile | HCID 23317862 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 4-Hydroxy-5,6,7,8-tetrahydronaphthalene-1-carbonitrile | HCID 23317864 | — |
Reaction Steps
4-Benzyloxy-5,6,7,8-tetrahydro-1-naphthonitrile (0.6 g, 2.3 mM) was hydrogenated in ethanol (30 ml) in the presence of 10% palladium on charcoal catalyst (100 mg). After 2 hours the catalyst was filtered off and the filtreate was evaporated to give the phenol (6) a white solid (0.4 g) mpt 133°-134° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04539319 |
| Source dataset | uspto-grants-1985_09 |
| ORD ID | ord-220079edfa4c43e29754cf4e885ac8ca |
| Source note | uspto-grants-1985_09 |