HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Chloro-2(1H)-pyrimidinone → HCID 15042725, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Chloro-2(1H)-pyrimidinone | HCID 108578 | — |
| Reactant | Methyl 4-[(chloromethoxy)methyl]benzoate | HCID 20267944 | — |
| Product | HCID 15042725 | HCID 15042725 | 62% |
Reaction Steps
was prepared as described in Example 3 from chloromethyl 4-methyloxycarbonylbenzyl ether (see Preparation 13) (8.8 mmol) and 5-chloropyrimidin-2-one (8.8 mmol) in 62% yield, m.p. 172° C. 1H NMR (CDCl3): δ3.92 (OMe), 4.77 (CH2Ph), 5.38 (CH2O), 7.2-8.2 (Ph), 7.78 asnd 8.50 (H-4, H-6, J 4 Hz).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04539324 |
| Source dataset | uspto-grants-1985_09 |
| ORD ID | ord-f3666bc94c53431d997b18c8201fc9f9 |
| Source note | uspto-grants-1985_09 |