HCID 13491506, compound → HCID 13491512, compound

Participants

Reaction Steps

Following the same procedure as described in Example 1, Step B, but substituting for the 1,2-bis-(3,4-dimethoxybenzoyl)ethane used therein, the 1-(3,4-dimethoxyphenyl)- 4-(2-naphthyl)butan-1,4-dione prepared above in Step A, there was obtained 370 mg of 2-(3,4-dimethoxyphenyl)-5-(2-naphthyl)tetrahydrofuran as a trans and cis mixture. This mixture was separated by HPLC to the cis-isomer (m.p. 74°-77° C.) and the trans-isomer (m.p. 112°-113° C.). PG,38 What is claimed is:

Provenance & Evidence