Epichlorohydrin → Diglycidyl ether

HRID 1719361Notes

Reaction equation

HRID 1719361 reaction equation
[OH:1][CH2:2][CH:3]1[O:8][C:7]2[CH:9]=CC=C[C:6]=2[O:5][CH2:4]1.C(C1OC1)Cl>>[CH2:6]([O:5][CH2:4][CH:3]1[O:1][CH2:2]1)[CH:7]1[O:8][CH2:9]1

Participants

3

Reactant 2

HCID 7835EpichlorohydrinHCID 193141,4-Benzodioxane-2-methanol

Product 1

HCID 16704Diglycidyl ether

Procedure

The novel process involves reaction of a 2-hydroxymethyl-1,4-benzodioxan with epichlorohydrin to produce an intermediate glycidyl ether, which is then reacted with a primary amine to produce the final 3-amino-1-[(1,4-benzodioxan)-2-yl-methoxy]-2-propanol or an acid addition salt thereof.

Sources & evidence

ORD record
ord-0c7963d7e03e4c57bf7eeb61b7e886a2
Source dataset
uspto-grants-1985_09
Patent number
US04539413

Reaction notes

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