HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Methoxy-N,N-dimethyl-1H-indole-3-methanamine → 5-methoxy-3-methyl-1H-indole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Methoxy-N,N-dimethyl-1H-indole-3-methanamine | HCID 27965 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 5-methoxy-3-methyl-1H-indole | HCID 11137444 | — |
Reaction Steps
A solution of 5-methoxygramine (3.96 g) in absolute ethanol (80 ml) with 10% Palladium on carbon (0.40 g) is hydrogenated at atmospheric pressure for 10 hours. The catalyst is removed by vacuum filtration through Hy-Flo and the filtrate is concentrated in vacuo to give an oil which crystallizes on standing to give 5-methoxy-3-methylindole.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04539410 |
| Source dataset | uspto-grants-1985_09 |
| ORD ID | ord-6cdae33fd9de43bfb99ee90950b755ec |
| Source note | uspto-grants-1985_09 |