HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methylamine → 1-[7-(N-methylcarbamoyl)heptyl]-3-methyl-2-(1-imidazolyl)indole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methylamine | HCID 6329 | — |
| Reactant | 1-(7-Ethoxycarbonylheptyl)-2-(1-imidazolyl)-3-methylindole | HCID 20268191 | — |
| Solvent | 1-Butanol | HCID 263 | — |
| Product | 1-[7-(N-methylcarbamoyl)heptyl]-3-methyl-2-(1-imidazolyl)indole | HCID 20268185 | — |
Reaction Steps
A solution of 4 g of 1-(7-ethoxycarbonylheptyl)-3-methyl-2-(1-imidazolyl)indole in 40 ml of n-butanol is saturated with methylamine and heated on a steam bath in a pressure bottle for 3 days. The reaction mixture is evaporated to dryness to yield 1-[7-(N-methylcarbamoyl)heptyl]-3-methyl-2-(1-imidazolyl)indole.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04539410 |
| Source dataset | uspto-grants-1985_09 |
| ORD ID | ord-3d7b797b164b418f99c8536cc827ddb1 |
| Source note | uspto-grants-1985_09 |