Pentyl nitrite → Amyl Acetate

Participants

Reaction Steps

To the same reaction vessel as in Example 9 were charged bistriphenylphosphinedibromopalladium (0.791 g, 1 mmole), stannous bromide (0.558 g, 2 mmoles) and tetra-n-ethylammonium bromide (0.420 g, 2 mmoles), together with n-amyl nitrite (50 ml, 356.0 mmoles) and chlorobenzene (200 ml). Then, nitrogen gas containing 10.0 vol.% of ketene and carbon monooxide were introduced to the mixture at the rate of 116.1 ml/min and 200 ml/min, respectively, and the reaction was performed at 90° C. for 3 hours. The reaction mixture was analyzed to reveal that di-n-amyl malonate (63.0 mmoles, 49.4%) and n-amyl acetate (36.5 mmoles, 28.3%) were obtained.

Provenance & Evidence