Boron tribromide → HCID 20268270, compound

HRID 1719430Notes

Reaction equation

HRID 1719430 reaction equation
C[O:2][C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][C:4]=1[NH:9][C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][C:11]=1[C:16](=[O:18])[CH3:17].B(Br)(Br)Br>C(Cl)Cl>[OH:2][C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][C:4]=1[NH:9][C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][C:11]=1[C:16](=[O:18])[CH3:17]

Participants

4

Reactant 2

HCID 25134Boron tribromide2×HCID 20268271HCID 20268271, compound

Product 1

HCID 20268270HCID 20268270, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent2×

Procedure

[I; R, R' and R"=H, OH at 2-position, Alk=CH3 ] is obtainable by reacting 1-[2-(2-methoxyphenylamino)phenyl]ethanone with boron tribromide. A preferred procedure comprises adding boron tribromide in an inert solvent such as methylene dichloride dropwise to a solution of the methoxy compound in an inert solvent, e.g. methylene dichloride cooled to a low temperature (-40° to -80° C.) and then stirring the mixture for several hours.

Workup

  1. temperaturecooled to a low temperature (-40° to -80° C.)

Sources & evidence

ORD record
ord-8562fca86d1349e4bba6863ac6cc1acd
Source dataset
uspto-grants-1985_09
Patent number
US04539429

Reaction notes

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