Ethanol → HCID 14485059, compound

HRID 1719490Notes

Reaction equation

HRID 1719490 reaction equation
[Br:1][CH2:2][CH2:3][C:4]1[CH:9]=[CH:8][C:7]([N+:10]([O-:12])=[O:11])=[CH:6][CH:5]=1.[CH2:13]([NH2:15])[CH3:14].C(O)C>>[BrH:1].[N+:10]([C:7]1[CH:8]=[CH:9][C:4]([CH2:3][CH2:2][NH:15][CH2:13][CH3:14])=[CH:5][CH:6]=1)([O-:12])=[O:11]

Participants

4

Reactant 3

HCID 702EthanolHCID 6341EthylamineHCID 792664-Nitrophenethyl bromide

Product 1

HCID 14485059HCID 14485059, compound

Procedure

1-Bromo-2-(4-nitrophenyl)ethane (Aldrich, 10 g, 50 mmol) was stirred overnight at ambient temperature with a solution of ethylamine in ethanol (33%, 25 ml, ~180 mmol). The orange solution was evaporated to leave a crystalline residue. The solid material was collected with the aid of ethanol (10 ml). Concentration of the filtrate yielded a second batch of product, identical on t.l.c., which was combined with the first.

Workup

  1. customThe orange solution was evaporated
  2. customto leave a crystalline residue
  3. customThe solid material was collected with the aid of ethanol (10 ml)
  4. customConcentration of the filtrate yielded a second batch of product

Sources & evidence

ORD record
ord-4fe6276aa9af41fa868c1eb40ccefb7e
Source dataset
uspto-grants-1985_09
Patent number
US04540682

Reaction notes

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