HCID 12557673, compound → HCID 54712699, compound

Participants

Reaction Steps

A mixture of methyl 4-hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxylate 1,1-dioxide (1.5 g) and 2-amino-5-chloro-2,4,6-cycloheptatrien-1-one (0.87 g) in xylene (37 ml) was refluxed for 24 hours. The reaction mixture was cooled to room temperature. The crystals were collected by filtration and recrystallized from N,N-dimethylformamide to give N-(5-chloro-1-oxo-2,4,6-cycloheptatrien-2-yl)-4-hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide (0.89 g).

Provenance & Evidence