HCID 13491471, compound → HCID 44283628, compound

Participants

Reaction Steps

A mixture of 2.0 g of 2-[(3,4-dihydro-1-methyl-2-naphthalenyl)methyl]-4,5-dihydro-1H-imidazole hydrochloride (Example 1b) and 200 mg of palladium-on-carbon catalyst in 100 ml of distilled water was hydrogenated until the mass spectrum showed no evidence of starting material. The product was isolated and recrystallized from ethanol to give 1.7 g of cis-4,5-dihydro-2-[(1,2,3,4-tetrahydro-1-methyl-2-naphthalenyl)methyl]-1H-imidazole in the form of its monohydrochloride salt, m.p. 214.5°-216° C.

Provenance & Evidence