Acetic Anhydride → HCID 86740298, compound

HRID 1719595Notes

Reaction equation

HRID 1719595 reaction equation
C([O-])(=O)C.[Na+].C(OC(=O)C)(=O)C.[Na:13].[S:14]([C:18]1[CH:23]=[CH:22][C:21]([N:24]2[C:29](=[O:30])[CH2:28][CH:26](O)[C:25]2=[O:31])=[CH:20][CH:19]=1)([OH:17])(=[O:16])=[O:15]>CCO.CC(C)=O>[Na:13].[S:14]([C:18]1[CH:19]=[CH:20][C:21]([N:24]2[C:29](=[O:30])[CH:28]=[CH:26][C:25]2=[O:31])=[CH:22][CH:23]=1)([OH:17])(=[O:15])=[O:16]

Participants

5

Reactant 3

HCID 7918Acetic AnhydrideHCID 517045Sodium AcetateHCID 86740299HCID 86740299, compound

Product 1

HCID 86740298HCID 86740298, compound

Reagents, catalysts & solvents 1

HCID 21889777Acetone ethanolSolvent

Procedure

A slurry of 0.8 g. sodium acetate (9.8 mmoles) and 16.0 g. II (54.6 mmoles) in 200 ml. acetic anhydride was refluxed until a color change to a tannish solution was noted. The solution was cooled to room temperature and diluted with 200 ml. EtOH:Acetone 3:2. The solution was filtered and the precipitate was slurried in an additional 200 ml. EtOH:Acetone 3:2 then filtered. The precipitate was dried under high vacuum giving 10.23 g. III (68.1%).

Workup

  1. additiondiluted with 200 ml
  2. filtrationThe solution was filtered
  3. filtrationEtOH:Acetone 3:2 then filtered
  4. customThe precipitate was dried under high vacuum
  5. customgiving 10.23 g

Sources & evidence

ORD record
ord-9515fdea087b422d874b292a881755a8
Source dataset
uspto-grants-1985_09
Patent number
US04540762

Reaction notes

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