HuagongsheHuagongshe Chemistry Print Report · For research reference only
(2R,3R,4S,5S)-2,3,4,5-tetrahydroxyhexanal → Hydrazine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (2R,3R,4S,5S)-2,3,4,5-tetrahydroxyhexanal | HCID 19233 | — |
| Reactant | 5-deoxy-L-arabinose-phenylhydrazone | HCID 68677317 | — |
| Reactant | HCID 178508811 | HCID 178508811 | — |
| Product | Hydrazine | HCID 9321 | — |
| Product | (6R)-2-amino-6-[(1R,2S)-1,2-dihydroxypropyl]-5,6,7,8-tetrahydro-1H-pteridin-4-one | HCID 178462349 | — |
Reaction Steps
1',2'-diacyl-L-biopterin of the general formula (III) can be prepared by converting L-rhamnose to an acyl derivative of 5-deoxy-L-arabinose-phenylhydrazone through a 1,1-dialkylsulfonyl-L-rhamnose, reacting the obtained acyl derivative with 2,4,5-triamino-6-hydroxy-pyrimidine to obtain a hydrazine derivative of tetrahydro-L-biopterin and oxidizing the hydrazine derivative, without isolating the intermediate products in the course of reaction from the 1,1-dialkylsufonyl-L-rhamnose to the 1',2'-diacyl-L-biopterin.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04540783 |
| Source dataset | uspto-grants-1985_09 |
| ORD ID | ord-eb6b5b0f8b6a4edab8535d2c57b89a96 |
| Source note | uspto-grants-1985_09 |