Acetic Anhydride → HCID 20267417, compound

HRID 1719647Notes

Reaction equation

HRID 1719647 reaction equation
[CH2:1]([C:6]1[CH:11]=[C:10]([O:12][CH3:13])[C:9]([O:14][CH3:15])=[CH:8][C:7]=1[OH:16])[CH2:2][C:3]([CH3:5])=[CH2:4].[C:17](OC(=O)C)(=[O:19])[CH3:18]>N1C=CC=CC=1>[C:17]([O:16][C:7]1[CH:8]=[C:9]([O:14][CH3:15])[C:10]([O:12][CH3:13])=[CH:11][C:6]=1[CH2:1][CH2:2][C:3]([CH3:5])=[CH2:4])(=[O:19])[CH3:18]

Participants

4

Reactant 2

HCID 7918Acetic AnhydrideHCID 20267416HCID 20267416, compound

Product 1

HCID 20267417HCID 20267417, compound

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Procedure

100 mg. of the phenol of Example 1 was combined with 2 ml. of pyridine and 1 ml. of acetic anhydride for one hour. The reaction mixture was extracted with ether and the ether extract washed sequentially with water, 1NHCl, water and saturated salt solution then dried over sodium sulfate. Upon evaporation 0.11 grams of the acetate was recovered.

Workup

  1. extractionThe reaction mixture was extracted with ether
  2. extractionthe ether extract
  3. washwashed sequentially with water
  4. dry with material1NHCl, water and saturated salt solution then dried over sodium sulfate
  5. customUpon evaporation 0.11 grams of the acetate
  6. customwas recovered

Sources & evidence

ORD record
ord-c4e5884db12846d197e6fd28c682f66f
Source dataset
uspto-grants-1985_09
Patent number
US04540830

Reaction notes

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