Water → HCID 53748468, compound

Participants

Reaction Steps

To a solution of 8.53 g of 3-(4-phenylthiobenzoyl)acrylic acid in 50 ml of dimethylformamide were added 4.54 g of dimethyl sulfate and 2.50 g of potassium carbonate, and the resulting mixture was stirred at room temperature for 3 hours. To the reaction solution was added water, and the mixture was extracted from diethyl ether. The organic layer was washed, in turn, with water, a saturated aqueous solution of sodium hydrogen-carbonate and water, and dried over magnesim sulfate. The diethyl ether was removed from the solution by evaporation, and the residue was recrystallized from a mixture of hexane and dichloromethane to give 6.80 g of methyl 3-(4-phenylthiobenzoyl)acrylate.

Provenance & Evidence