Propylene Oxide → HCID 86740305, compound

HRID 1719671Notes

Reaction equation

HRID 1719671 reaction equation
[P:1]([O-:8])([O:5]CC)[O:2][CH2:3][CH3:4].[I-].[CH3:10][S+:11]([CH3:13])[CH3:12].C1OC1C>O>[CH2:3]([O:2][P:1]([O-:8])[O-:5])[CH3:4].[CH3:10][S+:11]([CH3:13])[CH3:12].[CH3:10][S+:11]([CH3:13])[CH3:12]

Participants

5

Reactant 3

HCID 6378Propylene OxideHCID 75127Trimethylsulfonium iodideHCID 3780918Diethylphosphite

Product 1

HCID 86740305HCID 86740305, compoundYield 149.9%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Conditions

Temperature
35 °C

Procedure

Diethyl phosphite (5.5 g) and trimethylsulfonium iodide (8.2 g) are dissolved in water (80 ml). Propylene oxide (20 ml) is added and the mixture is then heated for 6 hours at 35° C. Concentration of the medium under reduced pressure gives a colorless oil (7.9 g) which crystallizes at ambient temperature. The crude product is dissolved in acetonitrile (25 ml) at ambient temperature. The solution is cooled by means of an acetone ice bath. The precipitated product is filtered off and then dried in a vacuum desiccator.

Sources & evidence

ORD record
ord-4bcfa4ec47bd44f386a25b2995feed38
Source dataset
uspto-grants-1985_09
Patent number
US04542023

Reaction notes

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