HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(4-Pyridyl)propane-1,2-diol → 2-(4-Piperidyl)propan-1,2-diol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(4-Pyridyl)propane-1,2-diol | HCID 20266430 | — |
| Catalyst | Platinum oxide (PtO) | HCID 82844 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | 2-(4-Piperidyl)propan-1,2-diol | HCID 20266396 | 101% |
Reaction Steps
A solution of 2-(4-pyridyl)propane-1,2-diol (2.0 g) in acetic acid (30 cm3) was hydrogenated over platinum oxide (0.10 g) at 60° and 60 p.s.i. pressure for 16 hours. The catalyst was removed by filtration through "Avicel" and volatile material was removed in vacuo to afford 2-(4-piperidyl)propan-1,2-diol (2.1 g). (Crude acetate salt, oil).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04542132 |
| Source dataset | uspto-grants-1985_09 |
| ORD ID | ord-50574a4a10134ecba160362d8832a05b |
| Source note | uspto-grants-1985_09 |