HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 1-Chloroethyl 5-(2,4-difluorophenyl)salicylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Phosphorus pentachloride | HCID 24819 | — |
| Reactant | Vinyl 5-(2,4-difluorophenyl)salicylate | HCID 20266755 | — |
| Product | 1-Chloroethyl 5-(2,4-difluorophenyl)salicylate | HCID 20266758 | — |
Reaction Steps
To a mixture of vinyl 5-(2,4-difluorophenyl)salicylate (15 g) and 0.1 g dry PCl5, HCl gas is passed for about one hour at about 120°-125° C. Upon cooling, the crude product crystallizes and is collected by filtration. Recrystallization from methanol yields pure 1-chloroethyl 5-(2,4-difluorophenyl)salicylate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04542158 |
| Source dataset | uspto-grants-1985_09 |
| ORD ID | ord-b93616667151484ebf06b7783337ada1 |
| Source note | uspto-grants-1985_09 |