HRID1719750

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID9737

2-Fluoroethanol

C2H5FO

HCID11789597

2,4-Imidazolidinedione, 3-(hydroxymethyl)-1-(2-propynyl)-

C7H8N2O3

$结构：CC1(C)[C@H](C(=O)O)[C@@H]1/C=C\C(=O)OCCF$

HCID86740321

未命名化合物

PRODUCTS

生成物

$结构：C#CCN1CC(=O)N(COC(=O)[C@@H]2[C@H](/C=C\C(=O)OCCF)C2(C)C)C1=O$

HCID86740320

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID6212

Chloroform

CHCl3

PROCEDURE

实验过程

Using the procedure of Step F of Example 9, (1R,cis) 2,2-dimethyl-3-[(Z) 3-oxo-3-(2-fluoroethoxy)-1-propenyl]-cyclopropane-carboxylic acid prepared as in Example 21 except 2-fluoroethanol was used and (3-propargyl-2,5-dioxo-imidazolidinyl)-methanol were reacted to obtain (3-propargyl-2,5-dioxo-1-imidazolidinyl)-methyl (1R,cis) 2,2-dimethyl-3-[(Z) 3-oxo-3-(2-fluoroethoxy)-1-propenyl]-cyclopropane-carboxylate with a specific rotation of [α]D20 =+18°±2° (c=1% in CHCl3)