HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Phenoxy-alpha-ethynylbenzylalcohol → alpha-ethynyl-3-phenoxy-benzyl(1R,cis)2,2-dimethyl-3-[(Z)3-oxo-3-(2-fluoroethoxy)-1-propenyl]-cyclopropane-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Phenoxy-alpha-ethynylbenzylalcohol | HCID 12919092 | — |
| Reactant | HCID 86740321 | HCID 86740321 | — |
| Solvent | Chloroform | HCID 6212 | — |
| Product | alpha-ethynyl-3-phenoxy-benzyl(1R,cis)2,2-dimethyl-3-[(Z)3-oxo-3-(2-fluoroethoxy)-1-propenyl]-cyclopropane-carboxylate | HCID 86740322 | — |
Reaction Steps
Using the procedure of Step F of Example 9, (1R,cis) 2,2-dimethyl-3-[(Z) 3-oxo-3-(2-fluoroethoxy)-1-propenyl]-cyclopropane-carboxylic acid and α-ethynyl-3-phenoxybenzyl alcohol were reacted to obtain α-ethynyl-3-phenoxy-benzyl (1R,cis) 2,2-dimethyl-3-[(Z) 3-oxo-3-(2-fluoroethoxy)-1-propenyl]-cyclopropane-carboxylate with a specific rotation of [α]D20 =+47°±1.5° (c=1% in CHCl3).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04542142 |
| Source dataset | uspto-grants-1985_09 |
| ORD ID | ord-37824c20d4524cfb8c823f95fbf17510 |
| Source note | uspto-grants-1985_09 |