Sodium Hydroxide → HCID 13408377, compound

Participants

Reaction Steps

0.3 grams of 1-methyl-2-(4-acetoxy-phenyl)-6-acetoxy-indole was dissolved in 20 cc of methanol, treated under nitrogen with 3 ml of 2N aqueous sodium hydroxide and stirred for 2 hours at room temperature. After acidification with 2N hydrochloric acid, the mixture was extracted by shaking with methylene chloride, dried and the solvent removed in a vacuum, the product was brought to crystallization with a little methylene chloride. Yield: 0.21 grams, M.P. 200°-204° C.

Provenance & Evidence