Hydrazinecarboxylic acid, ethyl ester → 2-(Ethoxycarbonylhydrazino)-6,7-dichloro-quinoxalin-3(4H)-one
Reaction equation
Cl[C:2]1[C:11](=[O:12])[NH:10][C:9]2[C:4](=[CH:5][C:6]([Cl:14])=[C:7]([Cl:13])[CH:8]=2)[N:3]=1.[C:15]([O:19][CH2:20][CH3:21])(=[O:18])[NH:16][NH2:17]>C(#N)C>[CH2:20]([O:19][C:15]([NH:16][NH:17][C:2]1[C:11](=[O:12])[NH:10][C:9]2[C:4](=[CH:5][C:6]([Cl:14])=[C:7]([Cl:13])[CH:8]=2)[N:3]=1)=[O:18])[CH3:21]Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Conditions
- Temperature
- 24 °C
Procedure
To a solution of 0.58 g (~2.3 mmol) 2,6,7-trichloroquinoxalin-3(4H)-one in 25 ml of acetonitrile was added 0.27 g (~2.6 mmol) of ethyl carbazate. The reaction mixture was refluxed for 3 h. Cooling to 24° C. gave the title compound (0.62 g; 84%) as a precipitate. M.p. >300° C. decomp.
Workup
- temperatureThe reaction mixture was refluxed for 3 h
Sources & evidence
- ORD record
- ord-848fc2b2816b465c94c4bcc8df5fe074
- Source dataset
- uspto-grants-1996_04
- Patent number
- US05504085
Reaction notes
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