HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrazine hydrate (1:1) → 3-Chloro-2-hydrazino-6-trifluoromethylquinoxaline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrazine hydrate (1:1) | HCID 24654 | — |
| Reactant | 2,3-Dichloro-6-(trifluoromethyl)quinoxaline | HCID 9970189 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 3-Chloro-2-hydrazino-6-trifluoromethylquinoxaline | HCID 19421438 | — |
| Product | 2-Chloro-3-hydrazino-6-trifluoromethylquinoxaline | HCID 22419804 | — |
Reaction Steps
The following two examples were prepared in an analogous manner from the appropriate 2(3)-chloro-3(2)-hydrazinoquinoxaline. The 2-Chloro-3-hydrazino-6-trifluoromethylquinoxaline and 3-chloro-2-hydrazino-6-trifluoromethylquinoxaline isomers were prepared from 2,3-dichloro-6-trifluoromethylquinoxaline by treatment with hydrazine hydrate in dichloromethane, and separated by column chromatography (silica gel) with toluenemethyl acetate (3:1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05504085 |
| Source dataset | uspto-grants-1996_04 |
| ORD ID | ord-d14003bab4ca4abaa52a3c5782ddd351 |
| Source note | uspto-grants-1996_04 |