HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzoyl Peroxide → 1-(Bromomethyl)-4-fluoro-2-nitrobenzene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzoyl Peroxide | HCID 7187 | — |
| Reactant | N-bromobutanimide | HCID 67184 | — |
| Reactant | 4-Fluoro-2-nitrotoluene | HCID 67965 | — |
| Solvent | Carbon Tetrachloride | HCID 5943 | — |
| Product | 1-(Bromomethyl)-4-fluoro-2-nitrobenzene | HCID 12761379 | — |
Reaction Steps
To a stirred solution of 4-fluoro-2-nitro toluene (48.9 g) and N-bromosuccinimide (56 g) in carbon tetrachloride (300 ml) was added benzoylperoxide (0.78 g). The mixture was heated under reflux for 90 minutes. Additionally, benzoylperoxide (0.78 g) was added to the mixture. Reflux was continued 90 minutes then, cooled to room temperature.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05504095 |
| Source dataset | uspto-grants-1996_04 |
| ORD ID | ord-75f22451642547eba7d5a1a1f12a4943 |
| Source note | uspto-grants-1996_04 |