HuagongsheHuagongshe Chemistry Print Report · For research reference only
Nitromethane → 5-Benzyl-3-(2-nitroethenyl)indole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Nitromethane | HCID 6375 | — |
| Reactant | Ammonium Acetate | HCID 517165 | — |
| Reactant | 5-Benzyl-3-formylindole | HCID 22419949 | — |
| Product | 5-Benzyl-3-(2-nitroethenyl)indole | HCID 54480700 | 34% |
Reaction Steps
The aidehyde 5-benzyl-3-formylindole (0.15 g, 0.6 mmol), nitromethane (0.9 ml) and ammonium acetate (0.05 g, 0.7 mmol) were heated gently under reflux for 0.5 h. On cooling, dark ruby-red crystals slowly separated. Crystallization from methanol gave 0.06 g (34%) of 5-benzyl-3-(2-nitroethenyl)indole as orange crystals.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05504101 |
| Source dataset | uspto-grants-1996_04 |
| ORD ID | ord-2d33d545fdde434f935645275ad74aa6 |
| Source note | uspto-grants-1996_04 |