1,4-Cyclohexanediol → ethyl N-{2-(4-hydroxycyclohexyloxycarbonyl)benzoyl)carbamate

HRID 1720123Notes

Reaction equation

[CH2:1]([O:3][C:4]([N:6]1[C:10](=[O:11])[C:9]2=[CH:12][CH:13]=[CH:14][CH:15]=[C:8]2[C:7]1=[O:16])=[O:5])[CH3:2].[CH:17]1([OH:24])[CH2:22][CH2:21][CH:20]([OH:23])[CH2:19][CH2:18]1>>[OH:23][CH:20]1[CH2:21][CH2:22][CH:17]([O:24][C:7]([C:8]2[CH:15]=[CH:14][CH:13]=[CH:12][C:9]=2[C:10]([NH:6][C:4](=[O:5])[O:3][CH2:1][CH3:2])=[O:11])=[O:16])[CH2:18][CH2:19]1

Participants

Reactant 2

HCID 111621,4-Cyclohexanediol

HCID 31187N-Carbethoxyphthalimide

Product 1

HCID 22420372ethyl N-{2-(4-hydroxycyclohexyloxycarbonyl)benzoyl)carbamate

Procedure

According to the same manner as described in Example 1 except for reacting N-ethoxycarbonylphthalimide with 1,4-cyclohexanediol under conditions shown in Table 19, ethyl N-{2-(4-hydroxycyclohexyloxycarbonyl)benzoyl)carbamate was obtained. Characteristics and identified structure of the resulting compound are shown in Table 10.

Sources & evidence

ORD record: ord-0337d8db5658441bb18e92a3f32b9011
Source dataset: uspto-grants-1996_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05504242

Reaction notes

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