反应详情

EP-B 0 042 119 also discloses a Comparative Example in which isophoronenitrile and liquid ammonia are pumped into the top of a hydrogenation reactor charged with commercially available cobalt catalyst. The reaction system is kept at 270 bar with H2 ; a certain gas stream is set up and a certain amount of off-gas is withdrawn. The reaction mixture leaving the bottom of the reactor is then worked up by distillation. Despite approximately quantitative conversion of the isophoronenitrile, this embodiment produces only 48% of isophoronediamine, together with many by-products. EP-B 0 042 119 does not suggest passing a mixture containing isophoronenitrile, ammonia and organic solvent, instead of a mixture of isophoronenitrile and ammonia, over a trickle bed reactor at an essentially low pressure and without the need for a preliminary imine formation reaction.

1. customare pumped into the top of a hydrogenation reactor
2. customa certain amount of off-gas is withdrawn
3. customThe reaction mixture leaving the bottom of the reactor
4. distillationis then worked up by distillation