Pyridine → HCID 22842888, compound

Participants

Reaction Conditions

Reaction Steps

To a solution of dry pyridine (0.46 ml) in methylene chloride (17.5 ml) cooled to -15° C. is added trifluoromethane sulfonic anhydride (0.87 ml). The mixture is stirred during 15 min at -10° C., then methyl 2,3,6-tri-O-benzyl-α-D-galacto-pyranoside (1.2 g, 2.58 mmol) in methylene chloride (5 ml) is added (N. Morishima, S. Koto, M. Oshima, A. Sugimoto and S. Zen, Bull. Chem. Soc. Jpn., 56, 2849 (1983)). The mixture is washed with water. The organic layer is dried over sodium sulfate, filtered and concentrated under reduced pressure so as to afford an oil which is the expected trillate methyl 2,3,6-tri-O-benzyl-4-O-trifluoromethyl-sulfonyl-α-D-galactopyranoside.

Provenance & Evidence