2,3-Dihydro-2-(phenyl)5-methyl-3-oxo-4-pyridazinecarbonitrile → 6-[(4-Chlorophenyl)thio]-2,3-dihydro-2-(3-methylphenyl)5-methyl-3-oxo-4-pyridazinecarbonitrile

HRID 1720252Notes

Reaction equation

HRID 1720252 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([S:8][C:9]2[C:10]([CH3:25])=[C:11]([C:23]#[N:24])[C:12](=[O:22])[N:13]([C:15]3[CH:20]=[CH:19][CH:18]=[C:17](Cl)[CH:16]=3)[N:14]=2)=[CH:4][CH:3]=1.Cl[C:27]1C=CC(SC2C(C)=C(C#N)C(=O)N(C3C=CC(Cl)=CC=3)N=2)=CC=1.ClC1C=CC(SC2C(C)=C(C#N)C(=O)N(C3C=CC=CC=3Cl)N=2)=CC=1.C1(N2C(=O)C(C#N)=C(C)C=N2)C=CC=CC=1>>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([S:8][C:9]2[C:10]([CH3:25])=[C:11]([C:23]#[N:24])[C:12](=[O:22])[N:13]([C:15]3[CH:20]=[CH:19][CH:18]=[C:17]([CH3:27])[CH:16]=3)[N:14]=2)=[CH:4][CH:3]=1

Participants

5

Reactant 4

HCID 118370772,3-Dihydro-2-(phenyl)5-methyl-3-oxo-4-pyridazinecarbonitrileHCID 152939216-[(4-Chlorophenyl)thio]-2,3-dihydro-2-(3-chlorophenyl)5-methyl-3-oxo-4-pyridazinecarbonitrileHCID 152939226-[(4-Chlorophenyl)thio]-2,3-dihydro-2-(4-chlorophenyl)5-methyl-3-oxo-4-pyridazinecarbonitrileHCID 224176836-[(4-Chlorophenyl)thio]-2,3-dihydro-2-(2-chlorophenyl)5-methyl-3-oxo-4-pyridazinecarbonitrile

Product 1

HCID 152954406-[(4-Chlorophenyl)thio]-2,3-dihydro-2-(3-methylphenyl)5-methyl-3-oxo-4-pyridazinecarbonitrile

Procedure

6-[(4-chlorophenyl)thio]-2,3-dihydro-2-(3-chlorophenyl)5-methyl-3-oxo-4-pyridazinecarbonitrile; 6-[(4-chlorophenyl)thio]-2,3-dihydro-2-(4-chlorophenyl)5-methyl-3-oxo-4-pyridazinecarbonitrile; 6-[(4-chlorophenyl)thio]-2,3-dihydro-2-(2-chlorophenyl)5-methyl-3-oxo-4-pyridazinecarbonitrile; 6-[(4-chloropheyl)thio]-(2,3-dihydro-2-(phenyl)5-methyl-3-oxo-4-pyridazinecarbonitrile;

Sources & evidence

ORD record
ord-336352bb31f54958a8f1bf20a8b25ebb
Source dataset
uspto-grants-1996_04
Patent number
US05506228

Reaction notes

Loading…