Hexylamine → 4-Hexylamino-2-methylquinolin-6-ol Hydrochloride

HRID 1720271Notes

Reaction equation

[Cl:1][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[C:9]([OH:12])[CH:10]=2)[N:5]=[C:4]([CH3:13])[CH:3]=1.[CH2:14]([NH2:20])[CH2:15][CH2:16][CH2:17][CH2:18][CH3:19]>>[ClH:1].[CH2:14]([NH:20][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[C:9]([OH:12])[CH:10]=2)[N:5]=[C:4]([CH3:13])[CH:3]=1)[CH2:15][CH2:16][CH2:17][CH2:18][CH3:19]

Participants

Reactant 2

HCID 8102Hexylamine

HCID 7715204-Chloro-2-methylquinolin-6-ol

Product 1

HCID 224179134-Hexylamino-2-methylquinolin-6-ol Hydrochloride

Procedure

In a manner similar to that described in Example 39, Part B, 4-chloro-2-methylquinolin-6-ol and hexylamine were transformed into the title compound: m.p. 234°-236° C.

Sources & evidence

ORD record: ord-b4fddeecb9304dff9f9332afaea3878e
Source dataset: uspto-grants-1996_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05506235

Reaction notes

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