Decylamine → 4-(Decylamino)quinolin-6-ol Hydrochloride

HRID 1720277Notes

Reaction equation

[Cl:1][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[C:9]([OH:12])[CH:10]=2)[N:5]=[CH:4][CH:3]=1.[CH2:13]([NH2:23])[CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH3:22]>>[ClH:1].[CH2:13]([NH:23][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[C:9]([OH:12])[CH:10]=2)[N:5]=[CH:4][CH:3]=1)[CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH3:22]

Participants

Reactant 2

HCID 8916Decylamine

HCID 184331324-Chloroquinolin-6-ol

Product 1

HCID 224179064-(Decylamino)quinolin-6-ol Hydrochloride

Procedure

In a manner similar to that described in Example 49, Part B, 4-chloroquinolin-6-ol and decylamine were transformed into the title compound as the hydrochloride salt: m.p. 197°-199° C.

Sources & evidence

ORD record: ord-0404c219956743cb99f2d810a6432efe
Source dataset: uspto-grants-1996_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05506235

Reaction notes

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