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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1720281Generated: November 1, 2026

4-(Cyclohexylmethoxy)aniline → 4-[4-(cyclohexylmethyloxy)phenylamino]quinolin-8-ol Hydrochloride Hydrate

https://huagongshe.com/reaction/1720281

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(Cyclohexylmethoxy)anilineHCID 15681651—
ReactantHCID 22417790HCID 22417790—
Product4-[4-(cyclohexylmethyloxy)phenylamino]quinolin-8-ol Hydrochloride HydrateHCID 22417823—

Reaction Steps

In a manner similar to that described in Example 46, Part B, 4-chloro-quinolin-8-ol hydrobromide and 4-(cyclohexylmethyloxy)aniline were tranformed into and the title product: m.p. 286°-288° C. (from methanol-acetonitrile).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05506235
Source datasetuspto-grants-1996_04
ORD IDord-e3c21f3082f24bbb925b62b0eea9dc76
Source noteuspto-grants-1996_04