Cyclooctanone → HCID 22923702, compound

HRID 1720299Notes

Reaction equation

HRID 1720299 reaction equation
[NH2:1][CH2:2][CH2:3][N:4]1[CH2:9][CH2:8][CH:7]([O:10][CH2:11][O:12][CH3:13])[CH2:6][CH2:5]1.[C:14]1(=O)[CH2:21][CH2:20][CH2:19][CH2:18][CH2:17][CH2:16][CH2:15]1>>[CH:14]1([NH:1][CH2:2][CH2:3][N:4]2[CH2:5][CH2:6][CH:7]([O:10][CH2:11][O:12][CH3:13])[CH2:8][CH2:9]2)[CH2:21][CH2:20][CH2:19][CH2:18][CH2:17][CH2:16][CH2:15]1

Participants

3

Reactant 2

HCID 10403CyclooctanoneHCID 22923703HCID 22923703, compound

Product 1

HCID 22923702HCID 22923702, compoundYield 90.9%

Procedure

Using 3 g of 1-(2-aminoethyl)-4-methoxymethoxypiperidine and 2 g of cyclooctanone, 4.3 g of 1-(2-cyclooctylaminoethyl)-4-methoxymethoxypiperidine was obtained in the same manner as in Reference Example 1.

Sources & evidence

ORD record
ord-355d88e896754dcda04f16cfd60703c6
Source dataset
uspto-grants-1996_04
Patent number
US05506239

Reaction notes

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