HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydroxyamine hydrochloride → 5-(4-Chlorobenzyl)-4-methoxymethyl-beta-carboline-3-carbaldehyde-oxime
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydroxyamine hydrochloride | HCID 443297 | — |
| Reactant | 5-(4-Chlorobenzyl)-4-methoxymethyl-beta-carboline-3-carbaldehyde | HCID 22417727 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | 5-(4-Chlorobenzyl)-4-methoxymethyl-beta-carboline-3-carbaldehyde-oxime | HCID 136375578 | 63.2% |
Reaction Steps
0.75 g (0.002 mol) of 5-(4-chlorobenzyl)-4-methoxymethyl-β-carboline-3-carbaldehyde is heated one hour to 105° C. with 0.18 g (0.0026 mol) of hydroxylaminehydrochloride in 19 ml of pyridine. 0.48 g (61% of theory) of 5-(4-chlorobenzyl)-4-methoxymethyl-β-carboline-3-carbaldehyde-oxime is obtained from the evaporation residue after recrystallization from ethanol, melting point 224°-228° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05506234 |
| Source dataset | uspto-grants-1996_04 |
| ORD ID | ord-4ef82d3220e143a983f691406fb0071d |
| Source note | uspto-grants-1996_04 |