HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrogen Peroxide → 5-Methoxy-2-methyl-1-oxo-1lambda~5~-pyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrogen Peroxide | HCID 784 | — |
| Reactant | 5-Methoxy-2-methylpyridine | HCID 13358777 | — |
| Catalyst | Manganese dioxide | HCID 14801 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | 5-Methoxy-2-methyl-1-oxo-1lambda~5~-pyridine | HCID 12214019 | — |
Reaction Steps
The 5-methoxy-2-picoline from Step 1 (6.7 g) was treated with 30% H2O2 (6.12 mL) in acetic acid (40 mL) at 100° C. overnight. After cooling to r.t., excess MnO2 was added and the slurry was stirred for 2 hours. Filtration and concentration in vacuo gave 7.0 g of the title N-oxide.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05506227 |
| Source dataset | uspto-grants-1996_04 |
| ORD ID | ord-e395fbb3e09b42e2887f7b19231d20dd |
| Source note | uspto-grants-1996_04 |