6-Methyl-2-pyridinecarboxaldehyde → 6-(Propan-2-yl)pyridine-2-carbaldehyde

HRID 1720368Notes

Reaction equation

[CH2:1]([C:3]1[N:8]=[C:7]([CH:9]=[O:10])[CH:6]=[CH:5][CH:4]=1)[CH3:2].[CH3:11]C1N=C(C=O)C=CC=1>>[CH:1]([C:3]1[N:8]=[C:7]([CH:9]=[O:10])[CH:6]=[CH:5][CH:4]=1)([CH3:11])[CH3:2]

Participants

Reactant 2

HCID 707376-Methyl-2-pyridinecarboxaldehyde

HCID 105347066-Ethylpicolinaldehyde

Product 1

HCID 193617556-(Propan-2-yl)pyridine-2-carbaldehyde

Procedure

The alkylation of 6-ethyl-2-pyridinecarboxaldehyde from Step 1 was performed as described above for 6-methyl,2-pyridinecarboxaldehyde.

Sources & evidence

ORD record: ord-3f5411fa6a524fe19fbc094d76f75e7d
Source dataset: uspto-grants-1996_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05506227

Reaction notes

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