(3,4-Dichlorophenoxy)acetic acid → HCID 22860078, compound

Participants

Reaction Steps

The title compound was prepared according to the method described in Example 2, using 3,4-dichlorophenoxyacetic acid (2.14 g, 9.7 mmol) and (±)-trans-N-methyl-N-[2-(1,2,3,4-tetrahydroisoquinolinyl)cyclohexyl]amine prepared in Example 17 (2.25 g, 9.2 mmol). The crude product was recrystallised from hot methanol, to give the title compound which was slightly hygroscopic. Yield 3.19 g (72%). Carbon-13 NMR data in accord.

Provenance & Evidence