HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 22418293, compound → HCID 22418301, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 22418293 | HCID 22418293 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | HCID 22418301 | HCID 22418301 | 64.3% |
Reaction Steps
By working in a way similar to that described in example 17 and by using N-(2-ethoxycarbonyl-4-pyrrolyl)-3-acetylthio-2-(3-methoxybenzyl)-propanamide (0.98 g; 2.42 mmoles), prepared as described in example 24, a crude was obtained which, chromatographed on silica gel (eluent CH2Cl2 :CH3OH:CH3COOH=90:10:1) and collected with ligroin:ethyl acetate=1:1 afforded N-(2-carboxy-4-pyrrolyl)-3-mercapto-2-(3-methoxybenzyl)-propanamide (0.520 g; 64.2% yield) as white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05506259 |
| Source dataset | uspto-grants-1996_04 |
| ORD ID | ord-4a3e5c50586c4948a736e172e273db1c |
| Source note | uspto-grants-1996_04 |