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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1720441Generated: October 25, 2026

Thiophene → E-N-[3-(5-(4-Fluorophenylmethyl)-fur-2-yl)-1-methyl-2-propenyl]-N-hydroxyurea

https://huagongshe.com/reaction/1720441

Reaction equation

Participants

RoleNameHCIDCharge
ReactantThiopheneHCID 8030—
ReactantCox/5-LO-IN-1HCID 9883481—
ReactantN-hydroxy-N-(butyn-2-yl)ureaHCID 19963264—
ProductE-N-[3-(5-(4-Fluorophenylmethyl)-fur-2-yl)-1-methyl-2-propenyl]-N-hydroxyureaHCID 22418459—

Reaction Steps

The desired compound is prepared according to the method of Example 2, except substituting furan for thiophene, and substituting N-(3-butyn-2-yl)N-hydroxyurea, prepared as in Example 3, step 2, for (R) N-(3-butyn-2-yl)N-hydroxyurea.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05506261
Source datasetuspto-grants-1996_04
ORD IDord-197e8b32c35b4a61b27832d814391a99
Source noteuspto-grants-1996_04