HuagongsheHuagongshe Chemistry Print Report · For research reference only
(2S)-1-(N-Benzyloxycarbonyl-L-prolyl)-2-[1-hydroxy-2-(phenylsulfinyl)ethyl]pyrrolidine → (2S)-1-(N-benzyloxycarbonyl-L-prolyl)-2-[(phenylsulfinyl)acetyl]-pyrrolidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (2S)-1-(N-Benzyloxycarbonyl-L-prolyl)-2-[1-hydroxy-2-(phenylsulfinyl)ethyl]pyrrolidine | HCID 57143389 | — |
| Reactant | Dmso dcc | HCID 86749402 | — |
| Product | (2S)-1-(N-benzyloxycarbonyl-L-prolyl)-2-[(phenylsulfinyl)acetyl]-pyrrolidine | HCID 15297817 | 79.4% |
Reaction Steps
(2S)-1-(N-Benzyloxycarbonyl-L-prolyl)-2-[1-hydroxy-2-(phenylsulfinyl)ethyl]pyrrolidine (850 mg) was subjected to DMSO-DCC oxidation as in Example 1-D) to give 672 mg of (2S)-1-(N-benzyloxycarbonyl-L-prolyl)-2-[(phenylsulfinyl)acetyl]-pyrrolidine (See Table 1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05506256 |
| Source dataset | uspto-grants-1996_04 |
| ORD ID | ord-ec50fb5da20f46b0b3a0d750d297158a |
| Source note | uspto-grants-1996_04 |